Alhydrogel

Product Presentation AlhydrogelTM

Alhydrogel is a sterilized aluminium hydroxide wet gel suspension which has been tested free of pyrogenicity. It tolerates re-autoclavation, but is destroyed if frozen.

 

When the pH is maintained at 5-7, which is normal during vaccine production, Alhydrogel has a positive charge so they readily adsorb negatively charged antigens (e.g. proteins with acidic isoelectric points kept at neutral pH).

 

Alhydrogel is available in three varieties: Alhydrogel 1.3%; Alhydrogel 2%  and Alhydrogel "85". For specifications of these products, please confer the specification table at page 8.

 

Alhydrogel 2% was elected as the International Standard Preparation for aluminium hydroxide gels at an independant scientific workshop in Greece in 1988 and 1990 (ref. Stewart-Tull 1989 and 1991).

 

With respect to final product analysis Alhydrogel comes in two series, one that complies with the original Brenntag Biosector specifications (“BBS-specification”) and a series that is produced in accordance with the same recipe and in principle identical, but tested for compliance with the specifications given in Ph.Eur. monograph 1664, launched in July 2004.

 

 

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